Products
Research-Grade Linear Plasmid DNA
Ready-to-order codon and UTR optimized linear plasmid DNA products produced using RNase-free proprietary purification methods with full endotoxin clearance.
Targets include:
- EGFP
- mCherry
- tdTomato
- Firefly Luciferase
- Cas9
- Human erythropoietin (EPO)
Research-Grade mRNA
Ready-to-order high quality mRNA products (capped and modified) produced using Northern RNA’s proprietary production methods including double-stranded RNA clearance for increased safety profile and reduced risk of immune-inflammatory reactions.
Targets include:
- EGFP
- mCherry
- tdTomato
- Firefly Luciferase
- Human erythropoietin (EPO)
Co Cap™ A
Co Cap™ A is an mRNA co-transcriptional cap analog that enhances the translational efficiency of mRNA molecules and protects against 5’ – 3’ exonuclease degradation.
- Cap analog - Ammonium salt of cap analog used in co-transcriptional capping of mRNA.
- 5’ Cap 1 mRNA – Use Co Cap™ directly in your mRNA IVT*.
- Flexible sizes – Available in 0.5, 1, 5, 10mL and custom pack sizes.
- Custom order – Sodium salt form and other Cap also available.
- Grade options – Research or GMP Grade available.
*Requires modified T7 RNA polymerase promoter
High Quality & Affordable
Co Cap ™ A is cost-effective and can support parallel development of your candidates. Our reagent is available in two grades (research and GMP) and will be able to carry your research and development all the way to commercial manufacturing.
- Consistent Quality – Co Cap ™ A’s proprietary manufacturing process ensures batch-to-batch consistency and high purity.
- Increase Efficacy – the use of Co Cap ™ results in mRNA molecules with a higher level of stability, leading to increased efficacy of mRNA-based therapeutics.
- Broad Applications – Co Cap is compatible with a wide range of mRNA-based therapeutic applications, including vaccines, gene therapies, and cancer treatments
| Assay | Method |
| Appearance | Visual Inspection |
| Concentration | UV Spectrophotometry |
| Identity (exact mass) | Mass Spectrometry |
| Identity (structure) | NMR Spectrometry (1H and 31P) |
| Purity | HPLC |
| pH | USP <791> |
| Conductivity | USP <644> |
| Endotoxin | Kinetic Chromogenic LAL |
| Bioburden | USP <61> |
| Residual Solvents | USP Residual Solvents: GC-MS |
| Elemental Impurities | ICP-MS |
| Ammonium Ion Concentration | Ion Chromatography |